Securing a seat in a top medical or dental college (MBBS/BDS) is the ultimate dream for thousands of pre-medical students in Pakistan. The MDCAT (Medical & Dental College Admission Test) conducted by PMDC through admitting universities like UHS, NUMS, SZABMU, and KMU is highly competitive and concept-driven.
According to the standard PMDC paper pattern, out of 200 total MCQs, Biology carries the highest weightage with 68 MCQs. If you master Biology, you secure the biggest chunk of your entry test score. To help you prepare effectively, we have curated a master list of 100 highly repeated FSc-level Biology MCQs from recent past papers.
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Open MDCAT Merit Calculator ➔MDCAT Biology Syllabus Focus Areas
- Cell Biology: Organelles, Mitosis/Meiosis, Fluid Mosaic Model.
- Bioenergetics & Enzymes: Photosynthesis, Respiration, Enzyme kinetics (Lock & Key, Induced Fit).
- Human Physiology: Digestion, Circulation, Nervous System, Immunity, and Hormones.
- Genetics & Evolution: Mendelian laws, DNA replication, Mutations, and Natural Selection.
Interactive MDCAT Biology Mock Test
Test your conceptual grip by attempting the 100 MCQs below. Click "Show My Result" at the end of the test to view your scorecard and read detailed explanations for all questions to clear your doubts.
📝 Interactive Practice Test (100 MCQs)
Exp: S.J. Singer and G.L. Nicolson proposed the Fluid Mosaic Model in 1972, which describes the cell membrane as a fluid lipid bilayer with embedded proteins.
Exp: Mitochondria are called powerhouses because they generate most of the cell's supply of adenosine triphosphate (ATP), used as a source of chemical energy.
Exp: Apoptosis is a highly regulated and controlled process of programmed cell death that occurs in multicellular organisms.
Exp: The nucleolus, located within the nucleus, is the site of ribosomal RNA (rRNA) transcription and processing, and of ribosome assembly.
Exp: Almost all enzymes are proteins, made up of chains of amino acids linked together by peptide bonds.
Exp: Emil Fischer proposed the Lock and Key model in 1894, suggesting that the enzyme's active site and the substrate fit together perfectly.
Exp: ATP (Adenosine Triphosphate) is the primary energy carrier in all living organisms on earth.
Exp: Glycolysis breaks down one molecule of glucose into two molecules of pyruvic acid (pyruvate), producing a net gain of 2 ATP.
Exp: Chloroplasts are the organelles found in plant cells and eukaryotic algae that conduct photosynthesis.
Exp: Vitamins A, D, E, and K are fat-soluble. Vitamins B and C are water-soluble.
Exp: The liver produces bile, which is then stored and concentrated in the gallbladder before being released into the small intestine to help digest fats.
Exp: The femur, or thigh bone, is the longest, heaviest, and strongest bone in the human body.
Exp: Alveoli are tiny, balloon-shaped air sacs in the lungs where the exchange of oxygen and carbon dioxide takes place.
Exp: The Sinoatrial (SA) node generates an electrical signal that causes the upper heart chambers (atria) to contract, acting as the natural pacemaker.
Exp: O negative blood has no A, B, or Rh antigens on the red blood cells, making it safe for transfusion to any other blood type.
Exp: The cerebellum coordinates voluntary movements such as posture, balance, coordination, and speech, resulting in smooth and balanced muscular activity.
Exp: The nephron is the microscopic structural and functional unit of the kidney responsible for filtering blood.
Exp: Insulin is a hormone produced by the beta cells of the islets of Langerhans in the pancreas to regulate blood glucose levels.
Exp: Adrenaline is released by the adrenal glands in response to stressful or exciting situations, preparing the body for a 'fight or flight' response.
Exp: A gene is the basic physical and functional unit of heredity, made up of DNA.
Exp: Human cells contain 23 pairs of chromosomes, for a total of 46. 22 pairs of autosomes and one pair of sex chromosomes.
Exp: Gregor Mendel, through his work on pea plants, discovered the fundamental laws of inheritance.
Exp: DNA has a double helix structure, discovered by James Watson and Francis Crick (with data from Rosalind Franklin).
Exp: Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.
Exp: Translation is the process in which ribosomes in the cytoplasm or ER synthesize proteins after the process of transcription.
Exp: Darwin proposed the theory of evolution by natural selection, outlined in his book "On the Origin of Species".
Exp: Paleontology is the scientific study of life that existed prior to, and sometimes including, the start of the Holocene Epoch (includes the study of fossils).
Exp: Binary fission is a form of asexual reproduction and cell division used by all prokaryotes (bacteria and archaea).
Exp: A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. It consists of genetic material (DNA or RNA) surrounded by a protein coat (capsid).
Exp: Malaria is caused by single-celled microorganisms of the Plasmodium group, transmitted by the bite of infected female Anopheles mosquitoes.
Exp: Antibiotics are antimicrobial substances active against bacteria. They do not fight viral infections like the common cold or flu.
Exp: Fungi cannot make their own food. They are heterotrophs, specifically decomposers (saprotrophs) that absorb nutrients from dead organic matter.
Exp: Magnesium is the central core atom in the chlorophyll molecule, essential for photosynthesis.
Exp: Xylem transports water and dissolved minerals from the roots to the rest of the plant. Phloem transports food (sugars).
Exp: Transpiration is the process of water movement through a plant and its evaporation from aerial parts, such as leaves, stems, and flowers.
Exp: The anther is the part of the stamen (male reproductive organ of a flower) where pollen is produced.
Exp: An adult human has 206 bones, whereas an infant is born with around 270 bones which later fuse together.
Exp: Blood is considered a fluid connective tissue because it has a matrix (plasma) and derives from mesenchyme.
Exp: Erythropoiesis (RBC production) occurs in the red bone marrow of large bones.
Exp: Human RBCs circulate for about 100 to 120 days before being destroyed by macrophages in the spleen and liver.
Exp: WBCs are called leukocytes. RBCs are erythrocytes, and platelets are thrombocytes.
Exp: The spleen is often called the "graveyard of RBCs" as it filters and destroys old or damaged red blood cells.
Exp: A normal blood pressure level is less than 120 systolic over less than 80 diastolic.
Exp: Salivary amylase begins the digestive process by breaking down starch into maltose.
Exp: The small intestine is covered with tiny projections called villi, which increase surface area for maximum nutrient absorption.
Exp: The stomach secretes HCl, which provides the acidic environment necessary for the enzyme pepsin to digest proteins.
Exp: Urea is formed in the liver through the urea cycle (from ammonia and carbon dioxide) and is then transported to the kidneys for excretion.
Exp: The neuron (nerve cell) is the fundamental unit of the brain and nervous system, responsible for receiving sensory input and sending motor commands.
Exp: A synapse is a small gap at the end of a neuron that allows a signal to pass from one neuron to the next.
Exp: The pituitary gland is called the master gland because its hormones control other parts of the endocrine system (like the thyroid, adrenals, and gonads).
Exp: A lack of dietary iodine causes the thyroid gland to enlarge (goiter) as it tries to trap as much iodine as possible.
Exp: Melanin is produced by cells called melanocytes. It protects the skin against sun damage and gives it its color.
Exp: Meiosis involves two rounds of cell division and results in four haploid daughter cells (gametes).
Exp: Mitosis occurs in somatic cells for growth and repair, producing two identical diploid daughter cells.
Exp: Crossing over (exchange of genetic material between homologous chromosomes) occurs during Prophase I, increasing genetic diversity.
Exp: Synapsis is the fusion of chromosome pairs at the start of meiosis.
Exp: Alleles are variant forms of the same gene located at the same position (locus) on a chromosome.
Exp: Phenotype refers to the observable physical properties of an organism, while genotype is its genetic makeup.
Exp: Human females have two X chromosomes (XX), while males have one X and one Y chromosome (XY).
Exp: Down syndrome is also known as Trisomy 21, because individuals have three copies of chromosome 21 instead of two.
Exp: DNA contains the sugar deoxyribose, whereas RNA contains the sugar ribose.
Exp: RNA uses Uracil (U) instead of Thymine (T). DNA uses Adenine, Thymine, Guanine, and Cytosine.
Exp: AUG is the start codon, which codes for the amino acid methionine. UAA, UAG, and UGA are stop codons.
Exp: B-lymphocytes (B cells) produce antibodies that bind to specific antigens on pathogens.
Exp: Vaccines stimulate the body's immune system to produce its own antibodies actively, but the exposure is artificial.
Exp: HIV (Human Immunodeficiency Virus) specifically infects and destroys CD4+ Helper T cells, weakening the immune system.
Exp: Carbon dioxide, methane, water vapor, and nitrous oxide are primary greenhouse gases that trap heat in the atmosphere.
Exp: CFCs released from older refrigerants and aerosols break down ozone molecules in the stratosphere.
Exp: A lichen is a mutualistic relationship between a fungus and an alga (or cyanobacterium). The fungus provides structure, while the alga provides food via photosynthesis.
Exp: Mycorrhizae are beneficial associations where fungi help plant roots absorb water and minerals, and the plant provides carbohydrates to the fungus.
Exp: Plasmids are small, circular, double-stranded DNA molecules distinct from a cell's chromosomal DNA, commonly found in bacteria and heavily used in genetic engineering.
Exp: PCR is a revolutionary technique used to make millions of copies of a specific DNA sample rapidly.
Exp: Restriction enzymes (endonucleases) act like molecular scissors, cutting DNA at specific recognition sites.
Exp: DNA ligase facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond.
Exp: Dolly the sheep was the first mammal cloned from an adult somatic cell (1996) using the process of nuclear transfer.
Exp: Plant cell walls are primarily made of cellulose. Fungal cell walls are made of chitin, and bacterial cell walls are made of peptidoglycan.
Exp: Animals store excess glucose in the liver and muscle cells in the form of glycogen. Plants store it as starch.
Exp: Transfer RNA (tRNA) serves as the physical link between the mRNA and the amino acid sequence of proteins.
Exp: The Electron Transport Chain, located on the inner mitochondrial membrane, produces the vast majority of ATP (around 32-34 molecules per glucose).
Exp: Through the process of photolysis in the light-dependent reactions, water molecules are split, releasing oxygen gas.
Exp: Chlorophyll absorbs red and blue light most efficiently for photosynthesis, while reflecting green light (which makes plants look green).
Exp: A population consists of interbreeding individuals of one species in a defined area.
Exp: A biological community consists of all the different interacting species (populations) in a specific habitat.
Exp: An ecological niche describes how an organism or population responds to the distribution of resources and competitors (its 'job' in the ecosystem).
Exp: Epithelial tissue covers the outside of the body and lines organs, vessels, and cavities.
Exp: Smooth muscle (found in the gut, blood vessels) is not under conscious control (involuntary) and lacks striations.
Exp: Bone, cartilage, blood, and adipose (fat) are all specialized types of connective tissue.
Exp: Interphase (G1, S, G2) is the longest phase, during which the cell grows and copies its DNA before entering mitosis (M phase).
Exp: During anaphase, the cohesin proteins are cleaved, and sister chromatids are pulled apart toward the cell poles.
Exp: Epistasis occurs when the effect of one gene is dependent on the presence of one or more 'modifier' genes.
Exp: In type AB blood, both the A and B alleles are fully expressed simultaneously, which is classic co-dominance.
Exp: A test cross is used to determine if an individual exhibiting a dominant trait is homozygous or heterozygous.
Exp: Lamarck proposed that organisms pass on traits acquired during their lifetime (e.g., a giraffe's long neck stretching over time). This theory was later largely disproved by modern genetics.
Exp: Homologous organs (like a human arm, whale flipper, and bat wing) share a common evolutionary ancestor but have adapted to different functions. Analogous organs have different origins but similar functions (insect wing vs bird wing).
Exp: Vestigial structures (like the human appendix or tailbone) are remnants of organs that were functional in evolutionary ancestors but are now non-functional or reduced.
Exp: The Domain (Archaea, Bacteria, Eukarya) is the highest taxonomic rank, broader than Kingdom.
Exp: Linnaeus established the system of giving organisms a two-part Latin name (Genus and species), such as Homo sapiens.
Exp: Prions are misfolded proteins that can transmit their misfolded shape onto normal variants of the same protein, causing diseases like Mad Cow Disease.
Exp: The pulmonary vein carries oxygen-rich blood from the lungs back to the left atrium of the heart. All other veins carry deoxygenated blood.
Exp: The larynx, commonly called the voice box, contains the vocal cords and produces sound.
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